Targeted Fat-Loss
Includes 2ml Bac Water vial
Purity: 99%
FRAG 176-191 is a modified fragment of the human growth hormone (HGH) protein, specifically a synthetic peptide comprising amino acids 176-191 of the C-terminus. This distinct region is recognized for its potent lipolytic activity, effectively mimicking the fat-reducing effects of HGH without engaging the receptors responsible for growth promotion or insulin-like growth factor 1 (IGF-1) mediation. Its selective action makes it a subject of significant interest in metabolic research.
FRAG 176-191 exerts its effects primarily by simulating the pituitary gland's natural HGH, specifically targeting adipocytes. It achieves this by increasing the expression of beta-3 adrenergic receptors, which enhances the breakdown of triglycerides into free fatty acids. Furthermore, it inhibits the activity of lipogenic enzymes, thus preventing the formation of new fat cells. This dual mechanism promotes the mobilization and oxidation of stored lipids.
Studies involving FRAG 176-191 explore its potential in metabolic regulation and the management of adiposity. Researchers investigate its capacity to induce targeted fat oxidation, particularly in models of diet-induced obesity, without confounding effects on glucose homeostasis or cellular proliferation. Its application is primarily centered on understanding selective lipolysis.
Elite Peptides guarantees FRAG 176-191 with a confirmed purity of ≥99% as verified through comprehensive third-party HPLC analysis. Our products are meticulously lyophilized and maintained under stringent cold-chain protocols to preserve stability and efficacy for research integrity.
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