$SLU-PP-332 ERR Agonist \| Exercise Mimetic for Metabolic Research \| High Purity \$

SLU-PP-332 ERR Agonist | Exercise Mimetic for Metabolic Research | High Purity

Exercise Mimetic

$49.95 AUD

Purity: 99%

SLU-PP-332 is a novel small molecule possessing pan-estrogen-related receptor (ERR) agonist activity. It selectively binds and activates ERRα, ERRβ, and ERRγ, nuclear receptors centrally involved in regulating metabolic homeostasis and mitochondrial function. This broad activation across the ERR subfamily underpins its potential as an exercise mimetic.

How It Works

Upon binding to ERRα, ERRβ, and ERRγ, SLU-PP-332 initiates a transcriptional program mimicking the cellular adaptations to endurance exercise. This involves upregulating genes associated with mitochondrial biogenesis, fatty acid oxidation, and oxidative phosphorylation. The resulting increase in mitochondrial density and efficiency contributes to improved metabolic flexibility and energy expenditure within various tissues.

Research Applications

Research into SLU-PP-332 primarily focuses on its capacity to enhance metabolic function and endurance pathways. Studies are exploring its effects on mitochondrial biogenesis, substrate utilization, and overall cellular energetics in various preclinical models. Its potential to modulate metabolic adaptability is a key area of investigation.

Why Elite Peptides

Elite Peptides provides SLU-PP-332 with a confirmed purity of ≥99% via High-Performance Liquid Chromatography (HPLC), meticulously verified by independent third-party laboratories. Our lyophilized product is shipped under stringent cold-chain conditions to ensure long-term stability and integrity.

Benefits

ERR Activation—SLU-PP-332 is a pan-agonist for the estrogen-related receptors (ERRα, ERRβ, and ERRγ), which are key regulators of cellular energy metabolism.
Mitochondrial Biogenesis—Pre-clinical studies have shown that activation of ERR receptors by SLU-PP-332 can stimulate the creation of new mitochondria in muscle cells.
Endurance Pathways—The compound mimics effects of endurance exercise by activating the PGC-1α and ERRα axis, a central pathway for muscle fiber type switching and oxidative metabolism.
Metabolic Flexibility—By activating ERR pathways, the compound may improve the capacity of cells to switch between different fuel sources, such as glucose and fatty acids.
Oxidative Capacity—Research indicates that ERR agonism can increase the expression of genes involved in oxidative phosphorylation, potentially enhancing cellular respiratory capacity.
Fatty Acid Oxidation—SLU-PP-332 may promote the breakdown of fatty acids for energy by upregulating genes involved in this process within muscle tissue.

Potential Side Effects

Limited Human Data—As a compound in the pre-clinical stage of research, there is no established human safety profile or list of common side effects.
Research Compound—This peptide is intended for laboratory research purposes only and not for human or veterinary use.
Unknown Long-Term Effects—The long-term consequences of systemic pan-ERR agonism in healthy, non-diseased systems have not been studied in humans.

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